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Medication Information: Proscar (Finasteride)

Uses of Proscar:

In adult men, Proscar is used to decrease an enlarged prostate (also known as benign prostatic hyperplasia or BPH). It can be used alone or in combination with other medications to alleviate BPH symptoms and possibly avoid surgery. Proscar (Finasteride) may help with BPH symptoms by reducing the need to urinate, improving urine flow with less straining, reducing the sense that the bladder isn't empty, and reducing overnight urination.

This medication works by lowering the quantity of DHT, a natural body hormone that drives prostate growth. Proscar isn't approved for prostate cancer prevention. It may raise the risk of acquiring a very dangerous form of prostate cancer by a small amount.

How to use Proscar?

• Take this medication by mouth once a day, with or without food, as instructed by your doctor.
• A pregnant woman or a woman who may become pregnant should not handle the tablet if it has been crushed or broken.
• To receive the best benefit from this medication, take it daily. It's important to remember to use it at the same time every day.
• It could take 6 to 12 months for you to observe a difference. If your illness does not improve or worsen, contact your doctor.

Side Effects of Proscar:

• You may lose your sexual ability or desire. This medicine may reduce the volume of semen released during intercourse in certain men.
• Proscar may also help you develop more hair.
• Serious side effects include such as a lump in your breast, nipple discharge, breast enlargement/tenderness/pain, testicular pain, or inability to pee.
• If you detect any symptoms of a major allergic response, such as a rash, itching/swelling (particularly of the face/tongue/throat), extreme dizziness, or problems breathing, seek medical treatment right away.

Proscar Precautions:

• If you are allergic to finasteride or have any other allergies, notify your doctor or pharmacist before taking it. Inactive chemicals may be included in this product, causing allergic reactions or other issues. For further information, speak with your pharmacist.
• Tell your doctor or pharmacist about your medical history, especially if you have liver disease, prostate cancer, infections, or urinary issues, before using this medication.
• Through the skin, the medicine can be absorbed. A woman who is pregnant or trying to become pregnant should not touch a tablet if the film coating has been damaged or the tablet has been crushed. Proscar exposure in a developing male child can cause genital malformations.
• Proscar should not be used by women, especially if they are pregnant or nursing. It has the potential to harm an unborn or nursing baby. If you have any questions regarding this medication, talk to your doctor.

Storage:

• Store at below 30-35 degrees C (86- 95 degrees F).
• Store in a cool, dry location away from direct sunlight and heat.
• Keep out of children's reach.

Proscar Drug interactions:

Keep a list of everything you use (including prescription and non-prescription pharmaceuticals, as well as herbal products) and discuss it with your doctor and pharmacist. Without your doctor's permission, do not begin, stop, or modify the dosage of any medications. The findings of a blood test used to identify prostate cancer may be influenced by this medicine (prostatic-specific antigen or PSA levels).

Safety and Tolerability:

When used in combination with Finasteride, this medicine may raise levels of DHT, a natural type of test that may help prevent and treat hair loss. Pregnant women should not use this drug because the potential risk is small and it may lead to serious problems in the unborn child.

Treatment for Prostate Cancer

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Objective:The aim of this study was to assess the clinical response rate of 5α-reductase inhibitors, such as finasteride and dutasteride, and to evaluate the efficacy of 5α-reductase inhibitors, such as finasteride and dutasteride, in the treatment of benign prostatic hyperplasia (BPH) in men with an enlarged prostate.

Materials and methods:This was a retrospective analysis of data from the Medicare National Health Service (MHNHS) and the National Health Service of the United Kingdom (NHS). The study was conducted by the authors of theNational Health Service Guideline for BPH.

Results:Of the 1,078 men, 1,054 (37.9%) experienced a clinically significant reduction in their prostate volume after receiving finasteride or dutasteride. The clinical response rate (CVR) to 5α-reductase inhibitors was significantly higher (p<0.0001) in the finasteride group than in the dutasteride group. The average CVR for the 5α-reductase inhibitor was 12.5% in the finasteride group and 18.8% in the dutasteride group.

Conclusion:The results of this study indicate that finasteride, and dutasteride, have comparable efficacy and safety profiles in treating benign prostatic hyperplasia (BPH) in men with an enlarged prostate.

Finasteride (Proscar®) and dutasteride (Dutasteride) - Clinical response rate and effect of 5α-reductase inhibitors: A retrospective cohort study.

A total of 5,834 men were treated with finasteride and dutasteride for the management of benign prostatic hyperplasia (BPH) in patients with an enlarged prostate. The primary outcome measures were the clinical response rate, the 5α-reductase inhibitor response, and the overall response rate. A total of 822 men were treated with finasteride and dutasteride. These were followed up over a mean of 4.5 years after baseline. The mean CVR of the 5α-reductase inhibitor was 12.5% in the finasteride group and 18.8% in the dutasteride group. The average CVR of the 5α-reductase inhibitor was 12.5% in the finasteride group and 18.8% in the dutasteride group. There was no significant difference between the finasteride group and dutasteride group in terms of the clinical response rate (p=0.77) or the 5α-reductase inhibitor response (p=0.56) as determined by the International Index of Erectile Function (IIEF). The median CVR of the 5α-reductase inhibitor in the finasteride group was 18.8% (IQR 8.0–26.2). The median CVR of the 5α-reductase inhibitor in the dutasteride group was 12.5% (IQR 8.0–25.9) and the median CVR of the 5α-reductase inhibitor in the finasteride group was 18.8% (IQR 8.0–25.9).

The results of this study show that the treatment response rates of the 5α-reductase inhibitor were significantly higher in the finasteride group than in the dutasteride group (p=0.0001). The difference between the 2 groups was not statistically significant. There was a significant difference in the overall response rate (p=0.0023) and CVR (p=0.0201) between the finasteride and dutasteride groups. The median CVR of the 5α-reductase inhibitor was 12.5% in the finasteride group and 18.8% in the dutasteride group.

Finasteride (Proscar®) and dutasteride (Dutasteride) - Effect of 5α-reductase inhibitors on the clinical response: A retrospective cohort study.

The results of this study show that the clinical response rate of 5α-reductase inhibitors was significantly higher in the finasteride group than in the dutasteride group (p=0.0004). The median CVR of the 5α-reductase inhibitor was 12.5% in the finasteride group and 18.

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OUT OF STOCKS PROSCAR BUT YOU MAY OPT TO BUY EQUIVALENT BRAND BUYING FOR EQUIVALENT BRAND AND SAVE: SAPHTERIDE/VEXFIN PROSCAR Out of Stocks Product variants BUYING FOR EQUIVALENT BRAND AND SAVE: SAPHTERIDE/VEXFIN - ₱14.00 PROSCAR Out of Stocks - Out of Stocks - ₱94.00

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Finasteride is used to treat men with benign prostatic hyperplasia (BPH) and male pattern hair loss, also called androgenetic alopecia. BPH is caused by an enlarged prostate. Men with BPH usually have difficulty urinating, a decreased flow of urination, hesitation at the beginning of urination, and a need to get up at night to urinate. Finasteride will make these symptoms less severe and reduce the chance that prostate surgery will be needed. It may be used alone or in combination with other medicines such as an alpha-blocker to treat BPH. For men with hair loss, finasteride will increase the number of scalp hairs but will not increase the amount of body hair.

Finasteride blocks the action of an enzyme called 5-alpha-reductase. This enzyme changes testosterone to another hormone that causes the prostate to grow or hair loss in males. It will increase testosterone levels in the body, which decreases prostate size and increases hair growth on the scalp. The effect of finasteride on the prostate and scalp will only last as long as the medicine is taken. When it is stopped, the prostate begins to grow again and the hair will be lost.

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